Palo Alto Prisma Access vs Cisco Secure Access -- SASE & Zero Trust Compared

Palo Alto Prisma Access vs Cisco Secure Access

Cisco Secure Access and Palo Alto Prisma Access are both sase & zero trust solutions. Cisco Secure Access cisco's unified SASE platform converging Umbrella, Duo, and Meraki into cloud-delivered security, while Palo Alto Prisma Access enterprise SASE platform extending Palo Alto's next-gen firewall to cloud-delivered security. The best choice depends on your organization's size, technical requirements, and budget.

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The Verdict

Choose Cisco Secure Access if cisco Talos provides massive threat intelligence from the world's largest commercial security research team is your priority and large enterprises with existing Cisco networking infrastructure wanting to consolidate security into a unified SASE platform. Choose Palo Alto Prisma Access if seamless policy extension for existing Palo Alto NGFW customers matters most and enterprises already invested in Palo Alto Networks firewalls that want to extend their security policies to a cloud-delivered SASE architecture.

Used Palo Alto Prisma Access or Cisco Secure Access? Share your experience.

Feature-by-Feature Comparison

FeatureCisco Secure AccessPalo Alto Prisma Access
PricingCustom enterprise pricing / Per-user or per-Mbps modelsCustom enterprise pricing / Per-user bundled subscription
Pricing ModelPer-user or bandwidth-based annual subscriptionPer-user annual subscription with bundled tiers
Open SourceNoNo
DeploymentCloudCloud
Best ForEnterprises already invested in Palo Alto Networks firewalls that want to extend their security policies to a cloud-delivered SASE architectureLarge enterprises with existing Cisco networking infrastructure wanting to consolidate security into a unified SASE platform
Umbrella DNS security and SWGNot availableSupported
Duo zero trust access and MFANot availableSupported
Meraki SD-WAN integrationNot availableSupported

When to Choose Each Tool

Choose Cisco Secure Access when:

  • +You value seamless policy extension for existing Palo Alto NGFW customers
  • +You value zTNA 2.0 provides continuous trust verification beyond initial authentication
  • +You value comprehensive SASE stack with integrated SD-WAN (Prisma SD-WAN)
  • +You want to avoid platform still maturing — recently converged from separate Umbrella, Duo, and AnyConnect products
  • +You want to avoid integration between acquired components can be inconsistent

Choose Palo Alto Prisma Access when:

  • +You value cisco Talos provides massive threat intelligence from the world's largest commercial security research team
  • +You value unified platform for organizations already invested in Cisco networking and security
  • +You value duo provides the most established zero trust MFA and access solution in the market
  • +You want to avoid most expensive SASE option with complex licensing and add-on costs
  • +You want to avoid not truly cloud-native — evolved from on-prem firewall architecture

Pros & Cons Comparison

Cisco Secure Access

Pros

  • +Cisco Talos provides massive threat intelligence from the world's largest commercial security research team
  • +Unified platform for organizations already invested in Cisco networking and security
  • +Duo provides the most established zero trust MFA and access solution in the market
  • +Meraki SD-WAN integration for branch office connectivity
  • +ThousandEyes provides industry-leading digital experience monitoring

Cons

  • Platform still maturing — recently converged from separate Umbrella, Duo, and AnyConnect products
  • Integration between acquired components can be inconsistent
  • Cloud-native SASE capabilities lag behind Zscaler and Netskope
  • Complex licensing with multiple SKUs inherited from different product lines
  • Inline inspection and SSL decryption less performant than purpose-built cloud proxies

Palo Alto Prisma Access

Pros

  • +Seamless policy extension for existing Palo Alto NGFW customers
  • +ZTNA 2.0 provides continuous trust verification beyond initial authentication
  • +Comprehensive SASE stack with integrated SD-WAN (Prisma SD-WAN)
  • +Strong threat prevention leveraging Palo Alto's Unit 42 threat intelligence
  • +Unified management for on-prem firewalls and cloud-delivered security

Cons

  • Most expensive SASE option with complex licensing and add-on costs
  • Not truly cloud-native — evolved from on-prem firewall architecture
  • Management complexity with multiple consoles (Panorama, Strata Cloud Manager)
  • Less compelling for organizations without existing Palo Alto investment
  • SD-WAN acquired (CloudGenix) and still being fully integrated

Sources & References

  1. Cisco Secure Access — Official Website & Documentation[Vendor]
  2. Palo Alto Prisma Access — Official Website & Documentation[Vendor]
  3. Cisco Secure Access Reviews on G2[User Reviews]
  4. Palo Alto Prisma Access Reviews on G2[User Reviews]
  5. Cisco Secure Access Reviews on TrustRadius[User Reviews]
  6. Palo Alto Prisma Access Reviews on TrustRadius[User Reviews]
  7. Cisco Secure Access Reviews on PeerSpot[User Reviews]
  8. Palo Alto Prisma Access Reviews on PeerSpot[User Reviews]
  9. Gartner Magic Quadrant for Single-Vendor SASE 2024[Analyst Report]
  10. Gartner Magic Quadrant for Security Service Edge 2024[Analyst Report]
  11. Forrester Wave: Zero Trust Network Access, Q3 2023[Analyst Report]
  12. IDC MarketScape: Worldwide SASE 2024[Analyst Report]
  13. CISA Zero Trust Maturity Model[Government Standard]
  14. Gartner Peer Insights: SSE[Peer Reviews]

Palo Alto Prisma Access vs Cisco Secure Access FAQ

Common questions about choosing between Palo Alto Prisma Access and Cisco Secure Access.

What is the main difference between Palo Alto Prisma Access and Cisco Secure Access?

Cisco Secure Access and Palo Alto Prisma Access are both sase & zero trust solutions. Cisco Secure Access cisco's unified SASE platform converging Umbrella, Duo, and Meraki into cloud-delivered security, while Palo Alto Prisma Access enterprise SASE platform extending Palo Alto's next-gen firewall to cloud-delivered security. The best choice depends on your organization's size, technical requirements, and budget.

Is Cisco Secure Access better than Palo Alto Prisma Access?

Choose Cisco Secure Access if cisco Talos provides massive threat intelligence from the world's largest commercial security research team is your priority and large enterprises with existing Cisco networking infrastructure wanting to consolidate security into a unified SASE platform. Choose Palo Alto Prisma Access if seamless policy extension for existing Palo Alto NGFW customers matters most and enterprises already invested in Palo Alto Networks firewalls that want to extend their security policies to a cloud-delivered SASE architecture.

How much does Cisco Secure Access cost compared to Palo Alto Prisma Access?

Cisco Secure Access pricing: Custom enterprise pricing / Per-user bundled subscription. Palo Alto Prisma Access pricing: Custom enterprise pricing / Per-user or per-Mbps models. Cisco Secure Access's pricing model is per-user annual subscription with bundled tiers, while Palo Alto Prisma Access uses per-user or bandwidth-based annual subscription pricing.

Can I migrate from Palo Alto Prisma Access to Cisco Secure Access?

Yes, you can migrate from Palo Alto Prisma Access to Cisco Secure Access. The migration process depends on your specific setup and the features you use. Both platforms offer APIs that can facilitate automated migration. Consider running both tools in parallel during the transition to ensure zero downtime.